Treatment and Pathophysiology of Pulmonary Hypertension

Patients with various forms of PH are cared for and actively involved in research projects within the framework of the Department of Pulmonology's focus on pulmonary hypertension (PH). We are are especially interested in the pathophysiological mechanisms that cause pulmonary hypertension and whether we can use certain therapies to limit the spread of the disease. Of particular interest is the cause of low blood oxygen in connection with PH; at night, during exercise and at high altitudes.

We are currently investigating the direct effect of oxygen therapy on performance during bicycle tests, on long-term endurance, as well as on oxygen levels in the brain and muscle tissues. Other research projects of ours are concerned with quality of life and the long-term course of the disease, while we also conduct clinical trials in collaboration with the pharmaceutical industry.

Current projects

TitleEthical approval numberClinical Trial Registration
​The efficacy and safety of initial triple versus initial dual oral combination therapy in patients with newly diagnosed pulmonary arterial hypertension
​2016-00146
​Acute hemodynamic and chronic clinical effects of acetazolamide in pulmonary hypertension
​2016-0089
LTOT-PH Effect of long-term oxygen therapy on exercise capacity and quality of life in patients with pulmonary arterial and chronic thromboembolic pulmonary hypertension2012-0538
Zurich Pulmonary Hypertension Outcome Assessment Cohort2014-0214
​Effect of exercise training in patients with pulmonary hypertension
​2015-0231
Asthma rehabilitation at high vs. low altitude - a randomized controlled trial
​2016-0076
​Effect of high altitude exposure, acclimatization and re-exposure on lung water content by ultrasound
Effect of high altitude exposure, acclimatization and re-exposure on right ventricular function in lowlanders



Information

Tel +41 44 255 22 20
Fax +41 44 255 85 17
pulmonalehypertonie@usz.ch

Team

Professor Silvia Ulrich, MD, Senior Attending Physician
Esther Schwarz, MD, Resident
Mona Lichtblau, MD, Resident
Charlotte Berlier, MD, Resident
Patrick Bader, MD, Research Assistant

Stéphanie Saxer, MSc, Research Assistant
Simon Schneider, BSc, Research Assistant
Alexandra Groth, MD, Doctorand
Simone Stickel, Study Nurse
Claudia Thalmann, Study Nurse
Christoph Jansen, Study Nurse
Mirjam Brenzikofer, Study Nurse
Isabel Schmied, Secretary
Conny Cajet, Secretary

Contact address

Department of Pulmonology
Professor Silvia Ulrich, MD
University Hospital Zurich
Rämistrasse 100
8091 Zurich

Last update: 22.06.2017 | Person responsible:
PD Silvia Ulrich, MD