Role of microRNAs in lung diseases

Several projects are currently studying the function of non-coding RNA - in particular microRNAs (miRNAs) - in connection with various lung diseases. miRNAs are small RNA fragments which possess no coding function but play an important role in gene regulation. It is estimated that miRNAs control the expression of more than 60% of the human genome.

Our laboratory is located on the new University of Zurich research campus at the Bio-Technopark, Zurich-Schlieren. The laboratory is fully equipped and allows for the implementation of all modern molecular biological methods (quantitative RT-PCR, ELISA, Western Blot, reporter gene assay, transfection, cell culture, immunohistochemistry).

Current Projects

TitleEthical approval numberClinical Trial Registration
microRNAs in diseases of the lung, airways and pulmonary vessels
151/2012 (Animal Ethics)
Aquaporines in hypoxia-induced pulmonary hypertension; expression and functionpendingn/a



Tel +41 44 255 39 26
Fax +41 44 255 89 97


Professor Malcolm Kohler, MD, Director of Department
PD Dr Lars C Huber, MD, Attending Physician
Matthias Brock, PhD, Research Assistant
Claudio Schuoler, MSc, Doctoral Student

Contact address

Research laboratory of the Department of Pulmonology
Bio-Technopark Schlieren-Zurich
Wagistrasse 14
8952 Zurich Schlieren


Last update: 22.06.2017 | Person responsible:
Professor Malcolm Kohler, MD