Cystic fibrosis

Cystic fibrosis (CF) is the most common genetic disease in Europe. Although the lungs are most frequently affected by the disease, it can also impact the pancreas, liver, gastrointestinal tract and other organs.

With advances in medicine, the survival rate of the CF population is now much higher than 10 years ago, although there is still no causal therapy. Today, more than half of the CF population lives beyond the age of 40. With the improved survival rates, CF has become a disease that also affects adults. According to the treatment guidelines of the European professional association (European Cystic Fibrosis Society, ECFC), these patients should receive care in specialized CF centers for adults.

Multidisciplinary treatment

The University Hospital Zurich has run a clinic for adults with CF for over 10 years. Almost 100 adult CF patients are currently being cared for, making the Zurich CF Center one of the largest in Switzerland. The CF clinic includes a multidisciplinary team. In addition to the three pulmonary physicians specialized in the treatment of CF patients, other specialist physicians and a CF-coordinator ("CF nurse"), the patients also receive comprehensive care from social counselors, nutritionists and a physiotherapist.

Lung transplantation for CF

In advanced CF lung disease, the ultimate therapeutic option is a lung transplantation. Over a third of all patients receiving lung transplantations through the Zurich lung transplantation program are individuals with CF. A lung transplantation not only increases their survival, but also improves their quality of life. The CF population benefits directly from the close cooperation between the CF team and the lung transplant team in Zurich.

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The Zurich CF team cooperates with other CF centers in Switzerland. For many years, the Children's Hospital of Zurich has offered a transition program for adolescent patients with CF.

The Zurich CF team also works together with CF centers abroad as well as with the European Cystic Fibrosis Society (ECFS). The Zurich CF centre together with the Children's Hospital of Zurich has been nominated as a novel member of the Clinical Trials Network of the ECFS.

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Consultation Cystic fibrosis
Current research on cystic fibrosis

Last update: 11.07.2019 | Person responsible:
Professor Malcolm Kohler, MD

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